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Basilea Pharmaceutica’s Phase 3 Study on Fosmanogepix: A Potential Game-Changer for Mold Infections

DEL_Basilea Pharmaceutica ((DEL_0QNA)), Basilea Pharmaceutica ((CH:BSLN)) announced an update on their ongoing clinical study.

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Study Overview: Basilea Pharmaceutica is conducting a Phase 3 study titled An Interventional Phase 3, Open-label, Two-cohort Study to Investigate the Efficacy and Safety of Fosmanogepix in Adult Patients With Invasive Mold Infections. The study aims to evaluate the efficacy and safety of fosmanogepix in treating invasive mold infections, a significant concern due to the severity and resistance of these infections.

Intervention/Treatment: The study tests fosmanogepix, administered either intravenously or orally, against standard antifungal treatments. Fosmanogepix is designed to treat invasive mold infections, offering a potential new option for patients who do not respond to existing therapies.

Study Design: This open-label, randomized study involves two cohorts: one receiving fosmanogepix and the other receiving standard care. The primary goal is to assess all-cause mortality by Day 42, providing critical insights into the treatment’s effectiveness.

Study Timeline: The study began in August 2025, with an estimated primary completion date yet to be announced. The last update was submitted in August 2025, indicating ongoing recruitment and progress.

Market Implications: The study’s progress could significantly impact Basilea Pharmaceutica’s stock, as successful results may enhance investor confidence and market position. The involvement of the Biomedical Advanced Research and Development Authority highlights the study’s importance in addressing drug-resistant infections, potentially setting Basilea apart from competitors.

The study is ongoing, with further details available on the ClinicalTrials portal.

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