AstraZeneca ((AZN)), AstraZeneca plc ((GB:AZN)), AstraZeneca ((DE:ZEGA)), AstraZeneca plc US ((AZNCF)) announced an update on their ongoing clinical study.
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AstraZeneca has launched a Phase III clinical trial, titled ‘A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination With Carboplatin Plus Pemetrexed Versus Platinum Plus Pemetrexed or Nivolumab Plus Ipilimumab in Participants With Unresectable Pleural Mesothelioma (eVOLVE-Meso)’. The study aims to evaluate the efficacy and safety of Volrustomig combined with Carboplatin and Pemetrexed against standard care options in treating unresectable pleural mesothelioma.
The study tests Volrustomig (MEDI5752), a drug administered via IV infusion, in combination with Carboplatin and Pemetrexed. This combination is compared to standard treatments, including Nivolumab plus Ipilimumab or platinum-based chemotherapy, to improve treatment outcomes for patients with this aggressive cancer.
This interventional study is randomized, open-label, and follows a parallel assignment model. It primarily focuses on treatment efficacy, with outcomes assessors being the only masked participants to ensure unbiased results.
The study began on November 9, 2023, with an estimated completion date in August 2025. These timelines are crucial for tracking the progress and expected data readouts, which could influence AstraZeneca’s strategic decisions and market performance.
The study’s progress could significantly impact AstraZeneca’s stock, as successful results may enhance its oncology portfolio and boost investor confidence. The competitive landscape includes other pharmaceutical giants also exploring treatments for mesothelioma, which could affect market dynamics.
The study is currently recruiting, with further details available on the ClinicalTrials portal.