AstraZeneca ((AZN)), AstraZeneca plc ((GB:AZN)), AstraZeneca ((DE:ZEGA)), AstraZeneca plc US ((AZNCF)) announced an update on their ongoing clinical study.
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AstraZeneca is conducting a Phase III study titled ‘CAMBRIA-1’ to evaluate the efficacy and safety of camizestrant, a next-generation oral selective estrogen receptor degrader, in patients with ER+/HER2- early breast cancer. The study focuses on patients who have completed at least two years of standard adjuvant endocrine therapy and are at intermediate or high risk of recurrence.
The intervention being tested is camizestrant, administered orally, compared against standard endocrine therapies such as tamoxifen and various aromatase inhibitors. The goal is to determine if camizestrant can improve outcomes in preventing breast cancer recurrence.
The study design is interventional, with a randomized, parallel assignment. There is no masking involved, and the primary purpose is treatment. Patients are randomly assigned to either continue standard endocrine therapy or switch to camizestrant.
The study began on March 31, 2023, and is currently recruiting participants. The primary completion and estimated study completion dates are set for July 1, 2025. These timelines are crucial for tracking the progress and potential market entry of camizestrant.
This study update could influence AstraZeneca’s stock performance positively if camizestrant shows significant benefits over existing therapies, potentially enhancing investor sentiment. The competitive landscape in breast cancer treatment is robust, with several companies vying for market share, making this study’s results particularly impactful.
The study is ongoing, with further details available on the ClinicalTrials portal.