AstraZeneca ((AZN)), Parexel International ((PRXL)), AstraZeneca plc ((GB:AZN)), AstraZeneca ((DE:ZEGA)), AstraZeneca plc US ((AZNCF)) announced an update on their ongoing clinical study.
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AstraZeneca, in collaboration with Parexel International, is conducting a Phase I clinical study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of AZD4248. This study targets healthy participants and those with chronic kidney disease and type 2 diabetes, aiming to assess the feasibility of home-based creatinine measurement.
The study involves the administration of AZD4248, both as an oral solution and intravenous infusion, to test its effects on participants. The primary goal is to determine the drug’s safety and effectiveness in managing diabetic kidney disease.
This randomized, single-blind, placebo-controlled study follows a sequential intervention model with double masking for participants and care providers. The primary purpose is treatment-focused, with parts of the study dedicated to different dosing regimens and participant groups.
The study began on June 9, 2025, with the latest update submitted on August 14, 2025. These dates are crucial for tracking the study’s progress and ensuring timely updates for stakeholders.
The outcome of this study could significantly impact AstraZeneca’s market position, potentially boosting investor confidence and stock performance if results are favorable. The study’s progress is closely watched by competitors and industry analysts, given its implications for diabetic kidney disease treatment.
The study is currently recruiting, with further details available on the ClinicalTrials portal.