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Assembly Biosciences Reports Positive Phase 1b Results

Story Highlights
  • Assembly Biosciences reported positive interim results from Phase 1b studies of ABI-1179 and ABI-5366.
  • The studies showed significant reductions in HSV-2 shedding and lesion rates, supporting further development.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Assembly Biosciences Reports Positive Phase 1b Results

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The latest announcement is out from Assembly Biosciences ( (ASMB) ).

On December 8, 2025, Assembly Biosciences announced positive interim results from Phase 1b clinical studies of its investigational herpes simplex virus (HSV) helicase-primase inhibitors, ABI-1179 and ABI-5366, for recurrent genital herpes. The studies demonstrated significant reductions in HSV-2 shedding rates and virologically confirmed genital lesion rates compared to placebo, with ABI-1179 showing a 98% reduction in shedding rate and ABI-5366 showing a 76% reduction. Both candidates were well-tolerated, and the company is progressing Phase 2 enabling activities for ABI-1179 and planning longer-duration Phase 2 studies for ABI-5366, potentially impacting their market positioning in the antiviral therapeutics sector.

The most recent analyst rating on (ASMB) stock is a Buy with a $50.00 price target. To see the full list of analyst forecasts on Assembly Biosciences stock, see the ASMB Stock Forecast page.

Spark’s Take on ASMB Stock

According to Spark, TipRanks’ AI Analyst, ASMB is a Neutral.

Assembly Biosciences faces significant financial challenges, with no revenue and persistent losses, heavily impacting its overall score. While technical indicators show bullish momentum, overbought signals suggest caution. Poor valuation metrics further weigh down the score, making it a risky investment.

To see Spark’s full report on ASMB stock, click here.

More about Assembly Biosciences

Assembly Biosciences, Inc. is a biotechnology company focused on developing innovative therapeutics targeting serious viral diseases.

Average Trading Volume: 136,550

Technical Sentiment Signal: Hold

Current Market Cap: $553.8M

Learn more about ASMB stock on TipRanks’ Stock Analysis page.

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