Agenus Inc. ((AGEN)) announced an update on their ongoing clinical study.
Meet Your ETF AI Analyst
- Discover how TipRanks' ETF AI Analyst can help you make smarter investment decisions
- Explore ETFs TipRanks' users love and see what insights the ETF AI Analyst reveals about the ones you follow.
A recent clinical study update from Agenus Inc. (AGEN) focuses on the combination of Vorbipiprant (CR6086) and Balstilimab (AGEN2034) in treating patients with refractory metastatic colorectal cancer (mCRC) and other metastatic gastrointestinal (GI) cancers. The study, officially titled An Open-label, Single-arm, Phase Ib/IIa Trial to Evaluate the Safety and Efficacy of the EP4 Receptor Antagonist Vorbipiprant (CR6086) in Combination With the PD-1 Inhibitor Balstilimab (AGEN2034), aims to assess the safety and efficacy of this combination therapy, particularly in patients with limited treatment options.
The interventions being tested include the drug CR6086 and the biological agent AGEN2034. CR6086 is administered orally twice a day, while AGEN2034 is given intravenously on the first day of each 14-day cycle. This combination is designed to target specific cancer pathways to improve patient outcomes.
The study employs a non-randomized, single-group design without masking, focusing on treatment as the primary purpose. It includes a dose escalation phase followed by a fixed-dose expansion phase to gather robust safety and efficacy data. The study is open-label, meaning both researchers and participants know the treatment being administered.
Key dates for the study include its start date on January 20, 2022, and an estimated completion date of May 28, 2025. These dates are crucial for investors to track progress and anticipate potential results that could impact market dynamics.
The update could influence Agenus Inc.’s stock performance and investor sentiment, as successful outcomes might enhance the company’s market position in the competitive oncology sector. Investors should also consider the broader industry context, including advancements by competitors in similar therapeutic areas.
The study is currently recruiting, with further details available on the ClinicalTrials portal.