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Spyre Therapeutics Slides Despite Bullish Long-Term Hopes

Spyre Therapeutics Slides Despite Bullish Long-Term Hopes

Spyre Therapeutics ( (SYRE) ) is experiencing volatility. Read on for a possible explanation for the stock’s unusual movement.

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Spyre Therapeutics’ stock is under pressure as investors reassess the risks around its pipeline and future milestones, even as analysts remain broadly constructive on the company’s long-term prospects. The main driver of sentiment is the company’s lead drug candidate for inflammatory diseases like rheumatoid arthritis, which targets the novel TL1A pathway and is seen as a potentially important innovation if successful. The ongoing SKYWAY Phase 2 trial is a critical catalyst, with proof-of-concept data expected in 2026 that could determine whether this new therapeutic approach gains traction. Despite current market weakness, analysts point to Spyre’s solid cash position and strong expert validation as support for the name and have maintained favorable price targets based on the potential upside from positive trial results.

More about Spyre Therapeutics

YTD Price Performance: 40.04%

Average Trading Volume: 971,718

Technical Sentiment Signal: Buy

Current Market Cap: $2.59B

For further insights into SYRE stock on TipRanks’ Stock Analysis page.

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