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Ionis Pharmaceuticals initiated with a Buy, named a top pick at Citi

Citi initiated coverage of Ionis Pharmaceuticals (IONS) with a Buy rating and $115 price target and named it a top pick among small-to-mid cap biotech stocks. Tryngloza for severe hypertriglyceridemia leads the higher value proprietary pipeline, with a greater than $3.5B peak sales opportunity “underappreciated,” the analyst tells investors. Partnered Phase 3 readouts offer opportunities for upside momentum in the second half of 2026, the analyst added.

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