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Jacobio Wins China KRAS Drug Approval and Strikes US$2 Billion AstraZeneca Deal

Story Highlights
  • Jacobio gained China approval and reimbursement listing for its KRAS G12C NSCLC drug glecirasib, while advancing key trials and publishing results in top journals.
  • Pan-KRAS candidate JAB-23E73 showed promising early pancreatic cancer data and attracted a US$100 million upfront, multi-billion AstraZeneca partnership.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Jacobio Wins China KRAS Drug Approval and Strikes US$2 Billion AstraZeneca Deal

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The latest update is out from Jacobio Pharmaceuticals Group Co., Ltd. ( (HK:1167) ).

Jacobio reported significant advances in its oncology pipeline, highlighted by Chinese regulatory approval of its KRAS G12C inhibitor glecirasib as a second-line monotherapy for NSCLC and its inclusion in the National Reimbursement Drug List. The company is also progressing a phase III first-line NSCLC study of glecirasib plus SHP2 inhibitor sitneprotafib, while expanding basket trials across multiple KRAS G12C-driven tumors and publishing key clinical results in leading medical journals.

In parallel, pan-KRAS inhibitor JAB-23E73 showed an encouraging safety profile and promising early efficacy in pancreatic cancer patients in a phase I trial in China, with a U.S. phase I study underway and a phase Ib/III trial cleared in combination with standard chemotherapy for first-line pancreatic ductal adenocarcinoma. Jacobio further strengthened its global positioning by signing a major licence and collaboration agreement with AstraZeneca for JAB-23E73, securing a US$100 million upfront payment and eligibility for up to US$1.915 billion in milestones plus tiered royalties, underscoring the strategic value of its KRAS franchise for investors and partners.

The most recent analyst rating on (HK:1167) stock is a Sell with a HK$5.00 price target. To see the full list of analyst forecasts on Jacobio Pharmaceuticals Group Co., Ltd. stock, see the HK:1167 Stock Forecast page.

More about Jacobio Pharmaceuticals Group Co., Ltd.

Jacobio Pharmaceuticals Group is a clinical-stage biopharmaceutical company focused on oncology, developing targeted small-molecule therapies against KRAS and SHP2 mutations. The company concentrates on innovative treatments for non-small cell lung cancer, colorectal cancer, pancreatic cancer and other solid tumors, with a growing emphasis on global partnerships and commercialization in China and abroad.

Average Trading Volume: 4,308,086

Technical Sentiment Signal: Sell

Current Market Cap: HK$4.82B

For detailed information about 1167 stock, go to TipRanks’ Stock Analysis page.

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