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Invion Expands INV043 Skin Cancer Trial to Basal Cell Carcinoma After Strong Safety Data

Story Highlights
  • Invion is advancing INV043 for non-melanoma skin cancers, expanding its trial to basal cell carcinoma patients after Safety Review Committee approval based on strong safety outcomes.
  • New squamous cell carcinoma data show no dose-limiting toxicities, reduced lesion sizes and complete responses in some cases, strengthening the case for Phase II development and broader theragnostic use.
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Invion Expands INV043 Skin Cancer Trial to Basal Cell Carcinoma After Strong Safety Data

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Invion ( (AU:IVX) ) has issued an update.

Invion has advanced its clinical program for INV043 in non-melanoma skin cancer by progressing to the final phase of its current trial and expanding enrolment to patients with basal cell carcinoma. This move follows approval from the Safety Review Committee, which was contingent on favourable safety data from earlier squamous cell carcinoma cohorts.

New preliminary data from six additional squamous cell carcinoma patients showed no dose-limiting toxicities, no treatment-related pain and strong tolerability relative to existing photodynamic therapies. The cohort also demonstrated statistically significant lesion size reductions, complete resolution in some cases and consistent fluorescence signals, reinforcing the theragnostic potential of INV043 and supporting Invion’s Phase II planning and a future anogenital trial using the same formulation.

More about Invion

Invion Limited is an Australia-based biotechnology company focused on developing INV043, a topical photodynamic therapy for non-melanoma skin cancers. The company targets conditions such as squamous cell carcinoma and basal cell carcinoma, aiming to address large, underserved dermatology markets with theragnostic treatment approaches.

Average Trading Volume: 79,546

Technical Sentiment Signal: Strong Sell

Current Market Cap: A$5.82M

For detailed information about IVX stock, go to TipRanks’ Stock Analysis page.

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