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Biogen’s Promising Phase 3 Trial: Felzartamab for Kidney Transplant Rejection

Biogen’s Promising Phase 3 Trial: Felzartamab for Kidney Transplant Rejection

Biogen Inc. ((BIIB)), Biogen ((CC:HTER)) announced an update on their ongoing clinical study.

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Biogen Inc. is currently recruiting participants for a Phase 3 clinical trial titled A Double-Blind, Placebo-Controlled, Multicenter, Randomized Phase 3 Trial Evaluating the Efficacy and Safety of Felzartamab in Kidney Transplant Recipients With Late Antibody-Mediated Rejection (AMR). The study aims to assess the effectiveness of felzartamab, a drug designed to treat late antibody-mediated rejection in kidney transplant recipients, compared to a placebo. This trial is significant as it addresses a critical need in transplant medicine, potentially improving outcomes for patients with AMR.

The intervention under investigation is felzartamab, an experimental drug administered via intravenous infusion. It is compared against a placebo, which is a 0.9% saline solution, to evaluate its efficacy in treating late AMR in kidney transplant recipients.

The study follows a randomized, parallel assignment model with quadruple masking, meaning that participants, care providers, investigators, and outcomes assessors are all blinded to the treatment allocation. The primary purpose of this interventional study is treatment-focused, aiming to provide insights into the therapeutic potential of felzartamab.

The trial began on December 3, 2024, with the latest update submitted on July 16, 2025. These dates are crucial as they mark the study’s progression and the timeline for potential results, which can influence investor decisions.

Biogen’s stock performance could be positively impacted by this study, as successful results may enhance their portfolio in the transplant rejection treatment market. Investors should monitor this trial closely, as a breakthrough could shift market dynamics and affect competitor positioning.

The study is ongoing, and further details can be accessed on the ClinicalTrials portal.

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