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Biogen’s Promising Phase 3 Trial: Felzartamab for Kidney Transplant Rejection

Biogen’s Promising Phase 3 Trial: Felzartamab for Kidney Transplant Rejection

Biogen Inc. ((BIIB)), Biogen ((CC:HTER)) announced an update on their ongoing clinical study.

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Biogen Inc. is conducting a significant Phase 3 clinical trial titled A Double-Blind, Placebo-Controlled, Multicenter, Randomized Phase 3 Trial Evaluating the Efficacy and Safety of Felzartamab in Kidney Transplant Recipients With Late Antibody-Mediated Rejection (AMR). The study aims to assess the effectiveness of felzartamab compared to a placebo in treating kidney transplant recipients experiencing late active or chronic active AMR, a condition that can lead to transplant failure.

The intervention being tested is felzartamab, an experimental drug administered via intravenous infusion, designed to treat late antibody-mediated rejection in kidney transplant patients. The trial also includes a placebo group receiving a saline solution for comparison.

This interventional study employs a randomized, parallel assignment model with quadruple masking (blinding of participants, care providers, investigators, and outcomes assessors) to ensure unbiased results. The primary purpose of the trial is treatment-focused, with Part A being randomized and placebo-controlled, followed by an open-label Part B.

The trial began on December 3, 2024, with the latest update submitted on June 30, 2025. These dates are crucial for tracking the study’s progress and ensuring transparency in its development.

The outcome of this study could significantly impact Biogen’s stock performance, as successful results may enhance investor confidence and position the company favorably against competitors in the kidney transplant treatment market. Investors will be keenly observing the trial’s progress and its implications for Biogen’s market strategy.

The study is currently ongoing, with further details available on the ClinicalTrials portal.

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